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Colonoscopic findings were abnormal in 58 patients (76%) showing mostly ulcerations and inflammation of the colon.Eighty nine percent of patients showed nonspecific inflammation with chronic inflammatory cells and half of these patients revealed the presence of granulomas and granulations on bowel biopsies.Correspondence to: Ibrahim A Al-Mofleh, Professor, Gastroenterology Division, Department of Medicine (38), King Khalid University Hospital, PO Box 2925 Riyadh 11461, Kingdom of Saudi Arabia Telephone: 966-1-4671215 Fax: 966-1-4672558AIM: To know the epidemiology and outcome of Crohn’s disease at King Khalid University Hospital, Riyadh, Saudi Arabia and to compare the results from other world institutions.METHODS: A retrospective analysis of patients seen for 20 years (between 19).Similarly, 69 (89%) of small bowel enema results revealed ulcerations (49%), narrowing of the bowel lumen (42%), mucosal thickening (35%) and cobblestone appearance (35%).CT scan showed abnormality in 68 (88%) of patients with features of thickened loops (66%) and lymphadenopathy (37%).CONCLUSION: The epidemiological characteristics of Crohn’s disease among Saudi patients are comparable to those reported from other parts of the world.

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Slight increase in mortality plays significant demands upon healthcare resources[1,2].

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.

The table below contains some of the most common ones associated with GTN rectal ointment.

Seventy-eight percent of patients had small and large bowel disease, 16% had small bowel involvement and only 6% had colitis alone.

Of the total 55 (71%) patients treated with steroids at some point in their disease history, a satisfactory response to therapy was seen in 28 patients (51%) while 27 (49%) showed recurrences of the condition with mild to moderate symptoms of abdominal pain and diarrhea most of which were due to poor compliance to medication.

Individual case records were reviewed with regard to history, clinical, findings from colonoscopy, biopsies, small bowel enema, computerized tomography scan, treatment and outcome.

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